Use for migraine, cost, how it works, etc.

Qulipta can cause mild or severe side effects. The following lists contain some of the main side effects that can occur when taking Qulipta. These lists do not include all possible side effects.

For more information about the possible side effects of Qulipta, talk to your doctor or pharmacist. They can give you advice on how to deal with side effects that may be concerning or bothersome.

To note: The Food and Drug Administration (FDA) tracks the side effects of drugs it has approved. If you want to notify the FDA about a side effect you have had with Qulipta, you can do so through MedWatch.

Mild side effects

Mild side effects* of Qulipta may include:

Most of these side effects may disappear within a few days or weeks. However, if they get worse or don’t go away, talk to your doctor or pharmacist.

*This is a partial list of mild Qulipta side effects. For more information about other mild side effects, talk to your doctor or pharmacist, or see the Qulipta prescribing information.
† For more information on this side effect, see “Details of side effects” below.

Serious side effects

Serious side effects from Qulipta have not been reported in clinical trials of the drug, but they may still occur. Call your doctor right away if you experience any serious side effects. Call 911 or your local emergency number if your symptoms are life-threatening or you think you have a medical emergency.

Allergic reaction is a possible serious side effect of Qulipta. For more information on this side effect, see “Details of side effects” below.

Details of side effects

Here are some details about some side effects that this drug can cause.

Nausea

In clinical trials, nausea was the most commonly reported side effect in people taking the drug. It was slightly more common in people who took higher doses of the drug.

It is important to note that nausea is also a common symptom of migraine episodes, which Qulipta is used to help prevent. It is still possible to have migraine episodes while taking Qulipta. (For more information on other medicines that can be used with Qulipta, see the “Using Qulipta with other medicines” section above.)

what you can do

Nausea from Qulipta may lessen as your body adjusts to the medication. Taking your daily dose with food may also help.

If you have bothersome or severe nausea while taking Qulipta, talk to your doctor about ways to manage this side effect. They may recommend taking a lower dose of Qulipta. Or they may suggest taking anti-nausea medications, such as ondansetron (Zofran) or promethazine (Phenergan).

Constipation

Constipation may occur when taking Qulipta. In clinical trials, constipation was among the most commonly reported side effects with the drug. It was slightly more common in people who took higher doses of the drug.

what you can do

You may be able to relieve constipation due to Qulipta simply by making lifestyle changes. These include getting enough gentle exercise, drinking plenty of fluids, and increasing the amount of fiber in your diet.

If you suffer from severe or persistent constipation, talk to your doctor or pharmacist. They may recommend taking a laxative medication. They may also recommend taking a lower dose of Qulipta.

Tiredness and weariness

Tiredness, fatigue, or drowsiness may occur while taking Qulipta. These side effects were among the most common side effects reported with Qulipta in clinical trials. They were slightly more common in people who took higher doses of the drug.

Keep in mind that you may also experience fatigue and tiredness before, during, and after a migraine episode. It is still possible to have migraine episodes while taking Qulipta. (For more information on other medicines that can be used with Qulipta, see the “Using Qulipta with other medicines” section above.)

what you can do

If you feel tired, tired or drowsy while taking Qulipta, you should not drive or engage in other potentially hazardous activities, such as operating machinery.

These side effects may subside as your body adjusts to the medication. However, if you suffer from tiredness or fatigue that is severe or bothersome, talk to your doctor or pharmacist. They may recommend a lower dose of Qulipta. Or they may recommend switching to another medication to help prevent the migraine.

Allergic reaction

No allergic reactions have been reported in clinical trials of Qulipta. However, as with most medicines, some people may have an allergic reaction after taking Qulipta.

Symptoms of a mild allergic reaction may include:

A more serious allergic reaction is rare but possible. Symptoms of a severe allergic reaction may include:

  • swelling under the skin, usually in the eyelids, lips, hands, or feet
  • swelling of the tongue, mouth or throat
  • difficulty breathing

Call your doctor right away if you have an allergic reaction to Qulipta, as the reaction could become serious. Call 911 or your local emergency number if your symptoms are life-threatening or you think you have a medical emergency.

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