Side effects, use for migraine, cost, etc.

Nurtec ODT can cause mild or severe side effects. The following lists contain some of the side effects that may occur when taking Nurtec ODT. But these lists do not include all possible side effects.

For more information about the possible side effects of Nurtec ODT, talk to your doctor or pharmacist. They can give you advice on how to deal with side effects that may be concerning or bothersome.

To note: The Food and Drug Administration (FDA) tracks the side effects of drugs it has approved. If you want to notify the FDA about a side effect you have had with Nurtec ODT, you can do so through MedWatch.

Mild side effects

Mild nausea is possible with the use of Nurtec ODT. This was the only mild side effect reported in a clinical study of the drug.* For more information on nausea, see “Details of side effects” below.

*To know more about other side effects of this medicine, talk to your doctor or pharmacist, or consult the Nurtec ODT patient information.

Serious side effects

Serious side effects from Nurtec ODT are not common, but they can occur. Call your doctor right away if you experience any serious side effects. Call 911 or your local emergency number if your symptoms are life-threatening or you think you have a medical emergency.

A hypersensitivity reaction is a rare but serious side effect that can occur with Nurtec ODT. This is a type of allergic reaction.

A hypersensitivity reaction was the only serious adverse reaction reported in clinical studies of Nurtec ODT. For more information, see “Details of side effects” below.

Details of side effects

You may be wondering how often side effects occur with this medication. Here are some details about some side effects it can cause.


Nausea was the most common side effect of Nurtec ODT in a clinical study.

This side effect may go away with continued use of Nurtec ODT. However, nausea is also a common migraine symptom.

In clinical studies, some people took rescue medication 2 hours after taking Nurtec ODT. Rescue medications are medications taken to relieve persistent migraine symptoms, such as pain, nausea, or vomiting.

Nausea after taking Nurtec ODT is usually manageable. But if it gets worse or doesn’t go away, talk to your doctor or pharmacist. They may recommend over-the-counter or prescription medication.

You can also try home remedies for migraine nausea relief or Nurtec ODT. Some options include:

  • rest in a cool, dark, quiet place
  • applying a cold compress or cold compress to the base of your head
  • to drink a lot of wateror drink ginger or chamomile tea
  • breathe in the smell of peppermint oil
  • eat a small bland snack, such as crackers or plain toast

Allergic reaction

As with most medicines, some people may have a hypersensitivity reaction (a type of allergic reaction) after taking Nurtec ODT. This is a rare but serious side effect that has occurred in clinical studies of the drug. Symptoms may include:

  • rash or hives
  • itching
  • redness (warmth, swelling, redness or discoloration of the skin)

More serious symptoms may take up to a few days to develop after taking Nurtec ODT. These symptoms can include:

  • swelling under the skin, usually in the eyelids, lips, hands, or feet
  • swelling of the tongue, mouth or throat
  • difficulty breathing

Symptoms may not develop for days after taking Nurtec ODT. So, continue to monitor symptoms for several days after taking a dose.

Call your doctor right away if you have symptoms of an allergic reaction, as the reaction could become serious. If your symptoms are mild, they may recommend medication to treat your reaction.

If you have severe symptoms, call 911 or your local emergency number. These symptoms could be life-threatening. If your doctor confirms that you have had a serious hypersensitivity reaction to Nurtec ODT, they will stop your treatment and recommend another migraine treatment.

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